BDBM50095131 (3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-carboxylic acid 4-[(3-chloro-benzoylamino)-methyl]-benzylamide::CHEMBL91872

SMILES CN1CC[C@H]([C@@H](C1)C(=O)NCc1ccc(CNC(=O)c2cccc(Cl)c2)cc1)c1ccc(Cl)cc1

InChI Key InChIKey=AQGDMGSGBMCAQM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095131   

TargetSodium-dependent serotonin transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50095131((3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...)
Affinity DataKi:  33nMAssay Description:Inhibition of [3H]5-HT uptake into rat synaptosomes by Serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50095131((3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...)
Affinity DataKi:  1.04E+3nMAssay Description:Inhibition of norepinephrine transporter by inhibition of [3H]NE uptake into rat nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50095131((3S,4R)-4-(4-Chloro-phenyl)-1-methyl-piperidine-3-...)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of [3H]DA uptake at Dopamine transporter into rat nerve endings (synaptosomes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed