BDBM50095172 CHEMBL262040::N-(3-Aminomethyl-phenyl)-thiophene-2-carboxamidine::N-[3-(aminomethyl)phenyl]thiophene-2-carboximidamide

SMILES NCc1cccc(NC(=N)c2cccs2)c1

InChI Key InChIKey=FODVLWUSSFCSRG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095172   

TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50095172(N-(3-Aminomethyl-phenyl)-thiophene-2-carboxamidine...)
Affinity DataKi:  8.70nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095172(N-(3-Aminomethyl-phenyl)-thiophene-2-carboxamidine...)
Affinity DataKi:  8.70nMAssay Description:Time dependent inhibition against neuronal Nitric Oxide Synthase(nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095172(N-(3-Aminomethyl-phenyl)-thiophene-2-carboxamidine...)
Affinity DataKi:  120nMAssay Description:Inhibition against induced Nitric Oxide Synthase(iNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095172(N-(3-Aminomethyl-phenyl)-thiophene-2-carboxamidine...)
Affinity DataKi:  460nMAssay Description:Inhibition against endothelial Nitric Oxide Synthase(eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed