BDBM50095172 CHEMBL262040::N-(3-Aminomethyl-phenyl)-thiophene-2-carboxamidine::N-[3-(aminomethyl)phenyl]thiophene-2-carboximidamide

SMILES NCc1cccc(NC(=N)c2cccs2)c1

InChI Key InChIKey=FODVLWUSSFCSRG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095172   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50095172(CHEMBL262040 | N-(3-Aminomethyl-phenyl)-thiophene-...)
Affinity DataKi:  8.70nMAssay Description:Inhibition of nNOS (unknown origin) assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095172(CHEMBL262040 | N-(3-Aminomethyl-phenyl)-thiophene-...)
Affinity DataKi:  8.70nMAssay Description:Inhibition against neuronal Nitric Oxide Synthase(nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095172(CHEMBL262040 | N-(3-Aminomethyl-phenyl)-thiophene-...)
Affinity DataKi:  120nMAssay Description:Inhibition against induced Nitric Oxide Synthase(iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095172(CHEMBL262040 | N-(3-Aminomethyl-phenyl)-thiophene-...)
Affinity DataKi:  460nMAssay Description:Inhibition against endothelial Nitric Oxide Synthase(eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed