BDBM50095179 CHEMBL447128::CHEMBL545487::N-(4-Amino-butyl)-pyrazole-1-carboxamidine; hydrochloride

SMILES NCCCCNC(=N)n1cccn1

InChI Key InChIKey=ZJUDHXNPQHGVCT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50095179   

TargetNitric oxide synthase, brain(Human)
Instituto De QuíMica MéDica

Curated by ChEMBL
LigandPNGBDBM50095179(CHEMBL545487 | CHEMBL447128 | N-(4-Amino-butyl)-py...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095179(CHEMBL545487 | CHEMBL447128 | N-(4-Amino-butyl)-py...)
Affinity DataKi:  6.00E+3nMAssay Description:Time dependent inhibition against neuronal Nitric Oxide Synthase(nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095179(CHEMBL545487 | CHEMBL447128 | N-(4-Amino-butyl)-py...)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition against induced Nitric Oxide Synthase(iNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50095179(CHEMBL545487 | CHEMBL447128 | N-(4-Amino-butyl)-py...)
Affinity DataKi:  4.60E+5nMAssay Description:Inhibition against endothelial Nitric Oxide Synthase(eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMed