BDBM50095230 5,7-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-3-carbonitrile::CHEMBL97463

SMILES COc1cc(OC)c2c(Nc3ccc(Oc4ccccc4)cc3)c(cnc2c1)C#N

InChI Key InChIKey=VYURVPVEVBZGHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095230   

LigandPNGBDBM50095230(5,7-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of ERK-phosphorylation by Raf-MEK-ERK in coupled ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50095230(5,7-Dimethoxy-4-(4-phenoxy-phenylamino)-quinoline-...)
Affinity DataIC50:  185nMAssay Description:Inhibition of ERK-phosphorylation by MEK-ERK in direct ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed