BDBM50095309 CHEMBL3589557

SMILES Cl.[H][C@]12CCCN1CCN(C2)C(=O)c1cc(c(F)cc1Cl)S(=O)(=O)Nc1ccccc1F

InChI Key InChIKey=KZRCYRFDOFTBHY-UHFFFAOYSA-N

Data  8 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50095309   

LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant Cav3.2 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of Cav3.2 channel in rat DRG neurons assessed as reduction in LVA currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of L-type calcium channel (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: 1.00E+4nMAssay Description:Competitive inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: 1.00E+4nMAssay Description:Competitive inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: 1.00E+4nMAssay Description:Competitive inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: 1.00E+4nMAssay Description:Competitive inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataIC50: 1.00E+4nMAssay Description:Competitive inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of PXR (unknown origin) assessed as induction of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50095309(CHEMBL3589557)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of aryl hydrocarbon receptor (unknown origin) assessed as induction of CYP1A2 mRNA expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2016
Entry Details Article
PubMed