BDBM50095449 2-[1-(2-Amino-ethyl)-6-(3-amino-propylamino)-hexylsulfanylmethyl]-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol::CHEMBL315995

SMILES NCCCNCCCCCC(CCN)SC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=IYEWZPHRHXRMCW-BWZSZYTASA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095449   

TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095449(2-[1-(2-Amino-ethyl)-6-(3-amino-propylamino)-hexyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Putrescine aminopropyltransferase (PAPT) in rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermine synthase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50095449(2-[1-(2-Amino-ethyl)-6-(3-amino-propylamino)-hexyl...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against spermine synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095449(2-[1-(2-Amino-ethyl)-6-(3-amino-propylamino)-hexyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of Spermidine aminopropyltransferase (SAPT) in rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed