BDBM50095626 Benzyl-[3-(3,4-dichloro-phenyl)-indan-1-yl]-methyl-amine;chloride::CHEMBL145994

SMILES Clc1ccc(cc1Cl)[C@@H]1C[C@@H](NCc2ccccc2)c2ccccc12

InChI Key InChIKey=FVVRXOHRSYEMTM-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095626   

TargetSodium-dependent dopamine transporter(Human)
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095626(Benzyl-[3-(3,4-dichloro-phenyl)-indan-1-yl]-methyl...)
Affinity DataKi:  80nMAssay Description:Binding affinity against cloned human dopamine transporter using 40-80 pM [125I]RTI.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095626(Benzyl-[3-(3,4-dichloro-phenyl)-indan-1-yl]-methyl...)
Affinity DataKi:  130nMAssay Description:Inhibition of reuptake of [3H]DA (20 nM) by dopamine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095626(Benzyl-[3-(3,4-dichloro-phenyl)-indan-1-yl]-methyl...)
Affinity DataKi:  380nMAssay Description:Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095626(Benzyl-[3-(3,4-dichloro-phenyl)-indan-1-yl]-methyl...)
Affinity DataKi:  460nMAssay Description:Binding affinity against norepinephrine cloned human transporter using 40-80 pM [125I]RTIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095626(Benzyl-[3-(3,4-dichloro-phenyl)-indan-1-yl]-methyl...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of reuptake of [3H]-NE (20 nM) by norepinephrine transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095626(Benzyl-[3-(3,4-dichloro-phenyl)-indan-1-yl]-methyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed