BDBM50096119 CHEMBL3593292

SMILES CCN1CCN(CC1)c1cc(Nc2ncc(s2)-c2ccc(NC(=O)Nc3cc(on3)C3CC3)cc2)nc(C)n1

InChI Key InChIKey=GCPZPTPTTRYEEE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096119   

TargetVascular endothelial growth factor receptor 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50096119(CHEMBL3593292)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant GST-tagged VEGFR2 kinase domain (V789 to V1356) (unknown origin) expressed in insect Sf9 cells using polyGlu4:Tyr peptide a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50096119(CHEMBL3593292)
Affinity DataIC50: 33nMAssay Description:Inhibition of wild type GST-tagged FLT3 kinase domain (Y567 to S993) (unknown origin) expressed in baculovirus infected insect Sf9 cells using Her2 p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50096119(CHEMBL3593292)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant GST-tagged Aurora-A kinase domain (S123 to S401) (unknown origin) expressed in insect Sf9 cells using tetra(LRRASLG) peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed