BDBM50096682 4-[(E)-2-(4,5-Diphenyl-thiazol-2-ylsulfamoyl)-vinyl]-benzoic acid methyl ester::CHEMBL110762

SMILES COC(=O)c1ccc(\C=C\S(=O)(=O)Nc2nc(c(s2)-c2ccccc2)-c2ccccc2)cc1

InChI Key InChIKey=HFFMZEZZMZXCMC-WUKNDPDISA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096682   

TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50096682(4-[(E)-2-(4,5-Diphenyl-thiazol-2-ylsulfamoyl)-viny...)
Affinity DataIC50:  2.60E+4nMAssay Description:In vitro inhibitory activity against human recombinant Cdc25B phosphatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50096682(4-[(E)-2-(4,5-Diphenyl-thiazol-2-ylsulfamoyl)-viny...)
Affinity DataIC50:  2.00E+4nMAssay Description:In vitro inhibitory activity against human recombinant VHR phosphatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50096682(4-[(E)-2-(4,5-Diphenyl-thiazol-2-ylsulfamoyl)-viny...)
Affinity DataIC50:  5.90E+4nMAssay Description:In vitro inhibitory activity against human recombinant PTP1B phosphatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed