BDBM50096701 (E)-2-(4-Trifluoromethyl-phenyl)-ethenesulfonic acid (4-biphenyl-4-yl-5-propyl-thiazol-2-yl)-amide::CHEMBL320953

SMILES CCCc1sc(NS(=O)(=O)\C=C\c2ccc(cc2)C(F)(F)F)nc1-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=VMOVWQJCIXPFMW-ISLYRVAYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096701   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50096701((E)-2-(4-Trifluoromethyl-phenyl)-ethenesulfonic ac...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity against human recombinant PTP1B phosphatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50096701((E)-2-(4-Trifluoromethyl-phenyl)-ethenesulfonic ac...)
Affinity DataIC50:  4.20E+4nMAssay Description:In vitro inhibitory activity against human recombinant VHR phosphatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50096701((E)-2-(4-Trifluoromethyl-phenyl)-ethenesulfonic ac...)
Affinity DataIC50:  9.20E+4nMAssay Description:In vitro inhibitory activity against human recombinant Cdc25B phosphatase enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed