BDBM50096710 (E)-2-(3,4-Difluoro-phenyl)-ethenesulfonic acid (4-biphenyl-4-yl-5-propyl-thiazol-2-yl)-amide::CHEMBL324669

SMILES CCCc1sc(NS(=O)(=O)\C=C\c2ccc(F)c(F)c2)nc1-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=NXEBTKYYJHMTFH-FOCLMDBBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096710   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50096710((E)-2-(3,4-Difluoro-phenyl)-ethenesulfonic acid (4...)
Affinity DataIC50:  7.70E+4nMAssay Description:In vitro inhibitory activity against human recombinant Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50096710((E)-2-(3,4-Difluoro-phenyl)-ethenesulfonic acid (4...)
Affinity DataIC50:  2.20E+4nMAssay Description:In vitro inhibitory activity against human recombinant Dual specificity protein phosphatase 3 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50096710((E)-2-(3,4-Difluoro-phenyl)-ethenesulfonic acid (4...)
Affinity DataIC50:  4.00E+4nMAssay Description:In vitro inhibitory activity against human recombinant Cell division cycle 25BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed