BDBM50096792 CHEMBL3580759

SMILES CN1CCN(C(=O)C[C@H](NC(=O)/C=C/c2cc(Cl)ccc2-n2cnnn2)c2nc(-c3ccc4[nH]c(=O)cc(O)c4c3)c(Cl)[nH]2)CC1

InChI Key InChIKey=NBMJTOOHXJGJNZ-UHFFFAOYSA-N

Data  13 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50096792   

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi:  0.100nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis at 37 degC by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi:  7nMAssay Description:Inhibition of plasma kallikrein (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi: >1.60E+3nMAssay Description:Inhibition of urokinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of trypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi: >9.00E+3nMAssay Description:Inhibition of coagulation factor 10a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of coagulation factor 7a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetCoagulation factor XII(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of coagulation factor 12a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi:  2.90E+4nMAssay Description:Inhibition of tPA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of tissue kallikrein (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi: >5.40E+4nMAssay Description:Inhibition of APC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50096792BDBM50096792(CHEMBL3580759)
Affinity DataKi: >6.00E+4nMAssay Description:Inhibition of coagulation factor 9a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2016
Entry Details Article
PubMed