BDBM50097235 (R)-N*1*-[(S)-2,2-Dimethyl-1-(1-methyl-1-phenyl-ethylcarbamoyl)-propyl]-N*4*-hydroxy-2-(3-phenyl-propyl)-succinamide::(R)-N1-((S)-3,3-dimethyl-1-oxo-1-(2-phenylpropan-2-ylamino)butan-2-yl)-N4-hydroxy-2-(3-phenylpropyl)succinamide::CHEMBL152855

SMILES CC(C)(C)[C@H](NC(=O)[C@H](CCCc1ccccc1)CC(=O)NO)C(=O)NC(C)(C)c1ccccc1

InChI Key InChIKey=XJTUBPYIIOWNPG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097235   

Target72 kDa type IV collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097235((R)-N1-((S)-3,3-dimethyl-1-oxo-1-(2-phenylpropan-2...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097235((R)-N1-((S)-3,3-dimethyl-1-oxo-1-(2-phenylpropan-2...)
Affinity DataIC50: 3.40nMAssay Description:Ability to inhibit the matrix metalloprotease-2 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097235((R)-N1-((S)-3,3-dimethyl-1-oxo-1-(2-phenylpropan-2...)
Affinity DataIC50: 72nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50097235((R)-N1-((S)-3,3-dimethyl-1-oxo-1-(2-phenylpropan-2...)
Affinity DataIC50: 73nMAssay Description:Ability to inhibit the matrix metalloprotease-3 by method of Knight et al using the fluorogenic peptide substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed