BDBM50097580 (6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid amide::CHEMBL2368218

SMILES [H][C@]12Cc3ccc(cc3[C@@](C)(CCN1CC1CC1)[C@H]2C)C(N)=O

InChI Key

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50097580   

TargetMu-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097580((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097580((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50097580((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.340nMAssay Description:Binding affinity to MOR (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50097580((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.420nMAssay Description:Binding affinity to KOR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097580((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]naltrindole from Opioid receptor delta 1 of guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50097580((6S,11R)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity to human DOR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed