BDBM50097792 (E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic acid::3-(2-(naphthalen-2-ylmethyl)phenyl)acrylic acid::CHEMBL423815

SMILES OC(=O)\C=C\c1ccccc1Cc1ccc2ccccc2c1

InChI Key InChIKey=MOLQZQYMXCCLHS-VAWYXSNFSA-N

Data  17 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50097792   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi:  20nMAssay Description:Antagonistic activity at Prostanoid EP3 receptor in human was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi:  47nMAssay Description:Binding affinity to EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi:  400nMAssay Description:Binding affinity to EP3 receptor in presence of HSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi: >500nMAssay Description:Binding affinity to IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi: >500nMAssay Description:Binding affinity to DP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi: >500nMAssay Description:Binding affinity to TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi: >500nMAssay Description:Binding affinity to FP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi:  530nMAssay Description:Antagonistic activity at Prostanoid DP receptor in human was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi:  3.10E+3nMAssay Description:Antagonistic activity at Prostanoid EP4 receptor in human was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi:  1.00E+4nMAssay Description:Antagonistic activity at Thromboxane A2 receptor in human was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi:  1.20E+4nMAssay Description:Antagonistic activity at Prostanoid EP2 receptor in human was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity to EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Canada

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity to EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi:  6.90E+4nMAssay Description:Antagonistic activity at Prostanoid FP receptor in human was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi: >1.00E+5nMAssay Description:Antagonistic activity at Prostanoid IP receptor in human was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50097792((E)-3-(2-Naphthalen-2-ylmethyl-phenyl)-acrylic aci...)
Affinity DataKi: >1.00E+5nMAssay Description:Antagonistic activity at Prostanoid EP1 receptor in human was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed