BDBM50097998 CHEMBL170726::{(R)-4-[(R)-4-Amino-5-(4-hydroxy-phenyl)-pyrrolo[2,3-d]pyrimidin-7-yl]-pyrrolidin-2-yl}-acetic acid ethyl ester

SMILES CCOC(=O)C[C@H]1C[C@@H](CN1)n1cc(-c2ccc(O)cc2)c2c(N)ncnc12

InChI Key InChIKey=SFUOPNLOTSTSRR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097998   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097998({(R)-4-[(R)-4-Amino-5-(4-hydroxy-phenyl)-pyrrolo[2...)
Affinity DataIC50: 100nMAssay Description:Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed