BDBM50098036 CHEMBL353289::N-Isopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyrazin-2-ylmethyl-acetamide

SMILES CC(C)N(Cc1cnccn1)C(=O)Cc1c([nH]c2ccccc12)-c1ccccc1

InChI Key InChIKey=LAXDTCKZLJVRNY-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098036   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50098036(N-Isopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyrazin-2...)Copy SMILESCopy InChI

Affinity DataIC50: 400nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/5/2012
Entry Details Article
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