BDBM50098190 22-cyclopropylmethyl-16-methoxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaen-2-amine::CHEMBL177194

SMILES COc1ccc2c3c1O[C@H]1c4[nH]c5ccccc5c4C[C@@]4(N)C(C2)N(CC2CC2)CCC314

InChI Key InChIKey=FMWAPMNLTHJZRN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098190   

TargetDelta-type opioid receptor(Human)
University of Bristol

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098190BDBM50098190(22-cyclopropylmethyl-16-methoxy-14-oxa-11,22-diaza...)
Affinity DataKi:  381nMAssay Description:Binding affinity to Opioid receptor delta 1 using [3H]DPDPE as a radioligand in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Bristol

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098190BDBM50098190(22-cyclopropylmethyl-16-methoxy-14-oxa-11,22-diaza...)
Affinity DataKi:  7.33E+3nMAssay Description:Evaluated for the binding affinity to Opioid receptor kappa 1 by using [3H]U-69593 as a radioligand in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Bristol

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098190BDBM50098190(22-cyclopropylmethyl-16-methoxy-14-oxa-11,22-diaza...)
Affinity DataKi:  1.47E+4nMAssay Description:Evaluated for the binding affinity to Opioid receptor mu 1 by using [3H]-DAMGO as a radioligand in guinea pigMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed