BDBM50098271 2-(4-Phenoxy-benzenesulfonylamino)-5-phenyl-pent-4-ynoic acid::CHEMBL10822

SMILES OC(=O)C(CC#Cc1ccccc1)NS(=O)(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=HCOFTHTVAIHKKV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50098271   

TargetCollagenase 3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098271(2-(4-Phenoxy-benzenesulfonylamino)-5-phenyl-pent-4...)
Affinity DataIC50:  2.15E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-13 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098271(2-(4-Phenoxy-benzenesulfonylamino)-5-phenyl-pent-4...)
Affinity DataIC50:  1.48E+3nMpH: 7.4Assay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2) in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098271(2-(4-Phenoxy-benzenesulfonylamino)-5-phenyl-pent-4...)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibitory activity against recombinant human matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098271(2-(4-Phenoxy-benzenesulfonylamino)-5-phenyl-pent-4...)
Affinity DataIC50:  4.56E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-3 (MMP-3) (at pH 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098271(2-(4-Phenoxy-benzenesulfonylamino)-5-phenyl-pent-4...)
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-1 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed