BDBM50098271 2-(4-Phenoxy-benzenesulfonylamino)-5-phenyl-pent-4-ynoic acid::CHEMBL10822
SMILES OC(=O)C(CC#Cc1ccccc1)NS(=O)(=O)c1ccc(Oc2ccccc2)cc1
InChI Key InChIKey=HCOFTHTVAIHKKV-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50098271
Affinity DataIC50: 2.15E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-13 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.48E+3nMpH: 7.4Assay Description:Inhibitory activity against matrix metalloproteinase-2 (MMP-2) in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibitory activity against recombinant human matrix metalloprotease-13More data for this Ligand-Target Pair
Affinity DataIC50: 4.56E+3nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-3 (MMP-3) (at pH 7.4)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Procter and Gamble Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMpH: 7.4Assay Description:Inhibitory activity against human matrix metalloproteinase-1 in quenched fluorescence assay at pH 7.4More data for this Ligand-Target Pair