BDBM50098380 (5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic acid::5-Hydroxy-5,5-bis-phosphono-pentyl-ammonium::5-amino-1-hydroxypentane-1,1-diyldiphosphonic acid::5-aminopentane-1-hydroxy-1,1-bisphosphonate::CHEMBL298771

SMILES NCCCCC(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=DXGBLRMRXHGUFX-UHFFFAOYSA-N

Data  3 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50098380   

TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)
Affinity DataKi:  48.2nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)
Affinity DataKi:  194nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)
Affinity DataKi:  420nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)
Affinity DataIC50:  4.37E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME? (M)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)
Affinity DataIC50:  299nMAssay Description:Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetFarnesyl pyrophosphate synthase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50098380((5-Amino-1-hydroxy-1-phosphono-pentyl)-phosphonic ...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed