BDBM50098387 CHEMBL3593274

SMILES Cl.OCC1(CCCNCC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=KETAPAGKHJIKAN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098387   

TargetSodium-dependent noradrenaline transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098387(CHEMBL3593274)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human NET expressed in CHOK1 cells incubated for 45 mins by [3H]-norepinephrine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098387(CHEMBL3593274)
Affinity DataIC50: 35nMAssay Description:Inhibition of human SERT expressed in CHOK1 cells incubated for 20 mins by [3H]-5-hydroxytryptamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50098387(CHEMBL3593274)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DAT expressed in CHOK1 cells incubated for 60 mins by [3H]-dopamine uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2016
Entry Details Article
PubMed