BDBM50098416 CHEMBL3593407

SMILES CC(C)[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(CNC(=O)C[C@H](NC1=O)\C=C\CCS)n2

InChI Key InChIKey=CPERKRDUKGURNJ-BNVDZZMOSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50098416   

TargetHistone deacetylase 1(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant full-length HDAC1 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 2(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of recombinant full-length HDAC2 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 8(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50:  255nMAssay Description:Inhibition of recombinant full-length HDAC8 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetHistone deacetylase 6(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50:  102nMAssay Description:Inhibition of recombinant full-length HDAC6 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone deacetylase 3(Human)
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50098416(CHEMBL3593407)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of recombinant full-length HDAC3 (unknown origin) using MAZ1600/MAZ1675 as substrate assessed as release of 7 amino-4-methylcoumarin measu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed