BDBM50098515 4-m-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxylic acid amide::CHEMBL269497

SMILES Cc1cccc(Sc2cncc3sc(cc23)C(N)=O)c1

InChI Key InChIKey=UACRFIVYIWIGPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098515   

TargetE-selectin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098515(4-m-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50: 45nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntercellular adhesion molecule 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098515(4-m-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50: 140nMAssay Description:In vitro potency against TNF alpha induced expression of intercellular adhesion molecule-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular cell adhesion protein 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098515(4-m-Tolylsulfanyl-thieno[2,3-c]pyridine-2-carboxyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro potency against TNF alpha induced expression of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed