BDBM50098596 CHEMBL3594313

SMILES CCS(=O)(=O)c1ccc2NC(=O)CCCc3ccc(cc3)[C@@H](Nc3ccc(cc3)C(N)=N)C(=O)NCc1c2

InChI Key InChIKey=HLENBKTVSREWEE-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50098596   

LigandPNGBDBM50098596(CHEMBL3594313)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human recombinant TF/F7a complex using S2288 as substrate preincubated for 15 mins followed by protein addition measured for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098596(CHEMBL3594313)
Affinity DataKi:  41nMAssay Description:Inhibition of human APC measured for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098596(CHEMBL3594313)
Affinity DataKi:  50nMAssay Description:Inhibition of human plasma kallikrein using S2302 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetTrypsin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098596(CHEMBL3594313)
Affinity DataKi:  58nMAssay Description:Inhibition of human trypsin measured for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098596(CHEMBL3594313)
Affinity DataKi:  180nMAssay Description:Inhibition of human thrombin using S2238 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetKallikrein-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098596(CHEMBL3594313)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human tissue kallikrein 1 measured for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098596(CHEMBL3594313)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of human F10a using S2222 as substrate measured for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50098596(CHEMBL3594313)
Affinity DataKi:  3.40E+4nMAssay Description:Inhibition of human F9a measured for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed