BDBM50098754 1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(1H-indol-6-ylsulfanyl)-phenyl]-propenone::CHEMBL281369

SMILES CC(=O)N1CCN(C(=O)/C=C/c2ccc(Sc3ccc4cc[nH]c4c3)c(Cl)c2)CC1

InChI Key InChIKey=MSANEFFUSIOKNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098754   

TargetIntegrin alpha-L/beta-2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50098754BDBM50098754(1-(4-Acetyl-piperazin-1-yl)-3-[3-chloro-4-(1H-indo...)
Affinity DataIC50: 150nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed