BDBM50098931 4,5-Dihydro-3H-benzo[c]azepin-1-ylamine::CHEMBL268668

SMILES NC1=NCCCc2ccccc12

InChI Key InChIKey=WPVIPLVHTUSDET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098931   

TargetNitric oxide synthase, brain(Rat)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098931(4,5-Dihydro-3H-benzo[c]azepin-1-ylamine | CHEMBL26...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of conversion of [3H]L-Arg to [3H]L-citrulline catalyzed by neuronal NOS (n NOS) from rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50098931(4,5-Dihydro-3H-benzo[c]azepin-1-ylamine | CHEMBL26...)
Affinity DataIC50: 1.20E+4nMAssay Description:Ability to inhibit conversion of [3H]L-Arg to [3H]L-citrulline catalyzed by endothelial NOS (e NOS) from HUVEC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed