BDBM50098950 5-Furan-2-yl-4,5-dihydro-thieno[2,3-c]pyridin-7-ylamine::CHEMBL274405
SMILES NC1=NC(Cc2ccsc12)c1ccco1
InChI Key InChIKey=WAOKDGZAIYAHLD-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50098950
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by n-NOS from rat cerebellumMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by e-NOS from HUVECcellsMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astrazeneca R&D Charnwood
Curated by ChEMBL
Astrazeneca R&D Charnwood
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Ability to inhibit the conversion of [3H]-L-Arg to [3H]-L-citrulline catalyzed by i-NOS from human DLD-1 cellsMore data for this Ligand-Target Pair