BDBM50099126 5-(4-Phenoxy-phenyl)-pyrimidine-2,4,6-trione::CHEMBL176517

SMILES Oc1[nH]c(=O)[nH]c(=O)c1-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=CVMFBMDAPZFQBR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099126   

TargetInterstitial collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099126(5-(4-Phenoxy-phenyl)-pyrimidine-2,4,6-trione | CHE...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099126(5-(4-Phenoxy-phenyl)-pyrimidine-2,4,6-trione | CHE...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of Gelatinase A, matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099126(5-(4-Phenoxy-phenyl)-pyrimidine-2,4,6-trione | CHE...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Gelatinase B, matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099126(5-(4-Phenoxy-phenyl)-pyrimidine-2,4,6-trione | CHE...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed