BDBM50099262 2-Phenyl-3-piperidin-3-yl-1H-indole::3-(Piperidin-3-yl)-2-phenyl-1H-indole::CHEMBL42557

SMILES C1CNCC(C1)c1c([nH]c2ccccc12)-c1ccccc1

InChI Key InChIKey=FYHCOUIJWCQUMZ-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50099262   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099262(3-(Piperidin-3-yl)-2-phenyl-1H-indole | 2-Phenyl-3...)
Affinity DataKi:  0.990nMAssay Description:Ability to displace [3H]ketanserin binding to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099262(3-(Piperidin-3-yl)-2-phenyl-1H-indole | 2-Phenyl-3...)
Affinity DataKi:  89nMAssay Description:Ability to displace [3H]mesulergine binding to human 5-hydroxytryptamine 2C receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099262(3-(Piperidin-3-yl)-2-phenyl-1H-indole | 2-Phenyl-3...)
Affinity DataKi: >1.30E+3nMAssay Description:Ability to displace [3H]spiperone binding to CHO cells stably expressing dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50099262(3-(Piperidin-3-yl)-2-phenyl-1H-indole | 2-Phenyl-3...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50099262(3-(Piperidin-3-yl)-2-phenyl-1H-indole | 2-Phenyl-3...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Tcg Lifesciences

Curated by ChEMBL
LigandPNGBDBM50099262(3-(Piperidin-3-yl)-2-phenyl-1H-indole | 2-Phenyl-3...)
Affinity DataKi:  4.90E+3nMAssay Description:Displacement of [3H]dofetilide from HEK cells expressing hERG voltage dependent IKr potassium channel Kv11.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed