BDBM50099406 CHEMBL3344272

SMILES CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NS(=O)(=O)Cc1ccccc1)C(C)C)[C@@H](O)CC(=O)NCCc1ccccc1

InChI Key InChIKey=PQZHZCPKSLRZNY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099406   

TargetPlasmepsin V(Plasmodium falciparum (isolate 3D7))
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099406BDBM50099406(CHEMBL3344272)
Affinity DataIC50: 19nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin V assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetPlasmepsin V(malaria parasite P. vivax)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099406BDBM50099406(CHEMBL3344272)
Affinity DataIC50: 24nMAssay Description:Inhibition of Plasmodium vivax plasmepsin V by fluorogenic PEXEL cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetCathepsin D(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099406BDBM50099406(CHEMBL3344272)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human cathepsin D assessed as cleavage of wtKAHRP fluorogenic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
The Walter and Eliza Hall Institute of Medical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50099406BDBM50099406(CHEMBL3344272)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human BACE1 assessed as cleavage of TRF substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed