BDBM50099465 (R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazolidine-4-carboxylic acid hydroxyamide::CHEMBL283580

SMILES ONC(=O)[C@H]1CN(Cc2ccc(Oc3ccc(F)cc3)cc2)C(=O)N1

InChI Key InChIKey=NBBPYGNNDFCNNP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099465   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50: 28nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50: 62nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50: 5.45E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed