BDBM50099487 2-(4-{2-[1-(2-Biphenyl-4-yl-ethyl)-3-cyclohexyl-ureido]-ethyl}-phenylsulfanyl)-2-methyl-propionic acid::CHEMBL280897

SMILES CC(C)(Sc1ccc(CCN(CCc2ccc(cc2)-c2ccccc2)C(=O)NC2CCCCC2)cc1)C(O)=O

InChI Key InChIKey=YPCVJZIGKJSYKB-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099487   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50099487(2-(4-{2-[1-(2-Biphenyl-4-yl-ethyl)-3-cyclohexyl-ur...)
Affinity DataEC50:  8nMAssay Description:In vitro transcriptional activation in CV-1 cells expressing human Gal4-PPAR alpha ligand binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50099487(2-(4-{2-[1-(2-Biphenyl-4-yl-ethyl)-3-cyclohexyl-ur...)
Affinity DataEC50:  2.40E+3nMAssay Description:In vitro transcriptional activation in CV-1 cells expressing human Gal4-PPAR gamma ligand binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50099487(2-(4-{2-[1-(2-Biphenyl-4-yl-ethyl)-3-cyclohexyl-ur...)
Affinity DataEC50:  5.00E+3nMAssay Description:In vitro transcriptional activation in CV-1 cells expressing human Gal4-PPAR delta ligand binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed