BDBM50099538 11-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-oxo-propyl}-2-methyl-isoindolo[2,1-a]indol-6-one::CHEMBL21788

SMILES COc1ccccc1N1CCN(CC1)C(=O)CCc1c2-c3ccccc3C(=O)n2c2ccc(C)cc12

InChI Key InChIKey=RKASKHITIDVOID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50099538   

TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099538(11-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-oxo-...)
Affinity DataIC50: 42nMAssay Description:Tested for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cells at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed