BDBM50099541 3-[2-(4-Bromo-phenyl)-1,5-dimethyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one::CHEMBL283318

SMILES COc1ccccc1N1CCN(CC1)C(=O)CCc1c(-c2ccc(Br)cc2)n(C)c2ccc(C)cc12

InChI Key InChIKey=UFWJRQHJIXUFAQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50099541   

TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099541(3-[2-(4-Bromo-phenyl)-1,5-dimethyl-1H-indol-3-yl]-...)
Affinity DataIC50: 0.140nMAssay Description:Tested for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cells at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed