BDBM50099551 1-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-[5-methyl-2-(4-trifluoromethyl-phenyl)-1H-indol-3-yl]-propan-1-one::CHEMBL278149

SMILES COc1ccccc1N1CCN(CC1)C(=O)CCc1c([nH]c2ccc(C)cc12)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=MHQFKUKAMZLTID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50099551   

TargetSubstance-P receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099551(1-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-[5-methy...)
Affinity DataIC50: 0.440nMAssay Description:Tested for displacement of [125I]-labeled substance P from cloned hNK1 receptor expressed in CHO cells at 100 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed