BDBM50099887 3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::CHEMBL282424

SMILES Fc1ccccc1N1CCN(Cc2c[nH]c3ncccc23)CC1

InChI Key InChIKey=OOKNJSVAHXTYKL-UHFFFAOYSA-N

Data  23 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 23 hits for monomerid = 50099887   

TargetD(4) dopamine receptor(Rat)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi:  3.30nMAssay Description:In vitro binding affinity to rat Dopamine receptor D4 measured by displacement of the radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi:  213nMAssay Description:In vitro binding affinity to human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi:  242nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi:  991nMAssay Description:In vitro binding affinity to human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Rat)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity to rat Dopamine receptor D2 measured by displacement of the radioligand [3H]-spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Rat)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity to cloned rat Dopamine receptor D3 measured by displacement of the radioligand [3H]-sulpirideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Muscarinic acetylcholine receptor M3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M2(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Muscarinic acetylcholine receptor M1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1E(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 1E receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(1B) dopamine receptor(Rat)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity to cloned rat D5 receptor measured by displacement of radioligand [3H]-SCH-23,982More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H1 receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(1A) dopamine receptor(Rat)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity to cloned rat Dopamine receptor D1 measured by displacement of radioligand [3H]-SCH-23,982More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M5(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Muscarinic acetylcholine receptor M5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:In vitro binding affinity to human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the compound to cloned Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1D(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 5A(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 5A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M4(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Muscarinic acetylcholine receptor M4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M2(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Human)
Columbia University College of Physicians and Surgeons

Curated by ChEMBL
LigandPNGBDBM50099887(3-[4-(2-Fluoro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to cloned human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed