BDBM50099917 4-[4-(4-Chloro-pyridin-3-yl)-thiazol-2-yl]-5-methylsulfanyl-thiophene-2-carboxamidine::CHEMBL28723

SMILES CSc1sc(cc1-c1nc(cs1)-c1cnccc1Cl)C(N)=N

InChI Key InChIKey=GVDWENUEEMSFBD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099917   

TargetUrokinase-type plasminogen activator(Human)
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099917(4-[4-(4-Chloro-pyridin-3-yl)-thiazol-2-yl]-5-methy...)
Affinity DataKi:  164nMAssay Description:Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetComplement C1s subcomponent(Human)
3-Dimensional Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099917(4-[4-(4-Chloro-pyridin-3-yl)-thiazol-2-yl]-5-methy...)
Affinity DataKi:  870nMAssay Description:Inhibitory activity against human Complement C1s subcomponent in erythrocyte hemolytic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed