BDBM50099999 1-(3-Chloro-phenyl)-4-[3-(3-phenoxy-benzyl)-3H-imidazol-4-ylmethyl]-piperazin-2-one::CHEMBL281695

SMILES Clc1cccc(c1)N1CCN(Cc2cncn2Cc2cccc(Oc3ccccc3)c2)CC1=O

InChI Key InChIKey=RAWVEDVPUJQLEN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099999   

LigandPNGBDBM50099999(1-(3-Chloro-phenyl)-4-[3-(3-phenoxy-benzyl)-3H-imi...)
Affinity DataIC50: 65nMAssay Description:In vitro inhibition against human Geranylgeranyl transferase type I catalyzed by incorporation of [3H]- GGPP (geranylgeranyl pyrophosphate) into biot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50099999(1-(3-Chloro-phenyl)-4-[3-(3-phenoxy-benzyl)-3H-imi...)
Affinity DataIC50: 1.23E+3nMAssay Description:In vitro inhibition against human Farnesyltransferase catalyzed by incorporation of [3H]- FPP into recombinant Ras-CVIMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed