BDBM50100011 CHEMBL1160386::Phosphoric acid 5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-2-phosphonooxymethyl-tetrahydro-furan-3-yl ester 4-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester

SMILES Nc1ccn([C@H]2C[C@H](OP(=O)(O)OC[C@H]3OC[C@@H](n4ccc(=O)[nH]c4=O)[C@@H]3O)[C@@H](COP(=O)(O)O)O2)c(=O)n1

InChI Key InChIKey=WGIAJLAXTLAWOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100011   

TargetIntegrase(Human immunodeficiency virus type 1)
The University of Iowa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100011BDBM50100011(Phosphoric acid 5-(4-amino-2-oxo-2H-pyrimidin-1-yl...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibitory concentration required against recombinant wild type HIV integrase by reproducible assay (Strand transfer)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
The University of Iowa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50100011BDBM50100011(Phosphoric acid 5-(4-amino-2-oxo-2H-pyrimidin-1-yl...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibitory concentration required against recombinant wild type HIV integrase by reproducible assay (Strand transfer)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed