BDBM50100308 4-Imidazol-1-ylmethyl-2-(3-phenylamino-phenoxy)-benzonitrile::CHEMBL25606

SMILES N#Cc1ccc(Cn2ccnc2)cc1Oc1cccc(Nc2ccccc2)c1

InChI Key InChIKey=IVHZRYBZVXHBJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100308   

LigandPNGBDBM50100308(4-Imidazol-1-ylmethyl-2-(3-phenylamino-phenoxy)-be...)
Affinity DataIC50: 17nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50100308(4-Imidazol-1-ylmethyl-2-(3-phenylamino-phenoxy)-be...)
Affinity DataIC50: 630nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed