BDBM50100309 2-(3-tert-Butyl-phenoxy)-4-imidazol-1-ylmethyl-benzonitrile::CHEMBL22710

SMILES CC(C)(C)c1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1

InChI Key InChIKey=BYWFNZWJIKYEJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100309   

LigandPNGBDBM50100309(2-(3-tert-Butyl-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50: 27nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50100309(2-(3-tert-Butyl-phenoxy)-4-imidazol-1-ylmethyl-ben...)
Affinity DataIC50: 520nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed