BDBM50100394 CHEMBL24687::[3-(2-Amino-thiazol-4-ylmethyl)-5-methoxy-2-methyl-indol-1-yl]-(4-chloro-phenyl)-methanone

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(Cc3csc(N)n3)c2c1

InChI Key InChIKey=IUNHGASZWHASJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100394   

TargetProstaglandin G/H synthase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100394([3-(2-Amino-thiazol-4-ylmethyl)-5-methoxy-2-methyl...)
Affinity DataIC50: 390nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 2 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100394([3-(2-Amino-thiazol-4-ylmethyl)-5-methoxy-2-methyl...)
Affinity DataIC50: 1.55E+7nMAssay Description:Inhibitory concentration against human recombinant Prostaglandin G/H synthase 1 cloned and expressed in baculovirus (Sf9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed