BDBM50101095 CHEMBL3325957

SMILES CN(C)[C@]1(c2ccccc2)CC[C@]2(CC1)OCCc1c3cc(F)ccc3[nH]c12

InChI Key InChIKey=CSMVOZKEWSOFER-UHFFFAOYSA-N

Data  8 KI  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50101095   

TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101095BDBM50101095(CHEMBL3325957)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]naloxone from human MOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101095BDBM50101095(CHEMBL3325957)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO-K1 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101095BDBM50101095(CHEMBL3325957)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human recombinant MOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by scintillation proxi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetKappa-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101095BDBM50101095(CHEMBL3325957)
Affinity DataKi:  2.60nMAssay Description:Binding affinity to human kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101095BDBM50101095(CHEMBL3325957)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human recombinant NOP receptor expressed in CHO-K1 cells assessed as stimulation of [35S]GTPgammaS binding by scintillation proxi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDelta-type opioid receptor(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101095BDBM50101095(CHEMBL3325957)
Affinity DataKi:  18nMAssay Description:Binding affinity to human delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50101095BDBM50101095(CHEMBL3325957)
Affinity DataKi:  480nMAssay Description:Inhibition of rat brain cortex L-type Ca2+-channel phenylalkylamine siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50101095BDBM50101095(CHEMBL3325957)
Affinity DataKi:  800nMAssay Description:Inhibition of rat brain cortex L-type Ca2+-channel benzothiazepine siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50101095BDBM50101095(CHEMBL3325957)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of rat whole brain L-type Ca2+-channel dihydropyridine siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pharmacokinetics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101095BDBM50101095(CHEMBL3325957)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2016
Entry Details Article
PubMed