BDBM50101236 2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-butylamino)-ethyl]-1H-indol-5-yl}-2-methyl-1-pyrrolidin-1-yl-propan-1-one::CHEMBL297703

SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1cccnc1)C(C)(C)C(=O)N1CCCC1

InChI Key InChIKey=NTZZUGUKBHYDIN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50101236   

TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50101236(2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-bu...)
Affinity DataIC50:  5nMAssay Description:Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50101236(2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-bu...)
Affinity DataIC50:  290nMAssay Description:Inhibition of GnRH-stimulated phosphatidyinositol (PI) hydrolysis in cloned chinese hamster ovary (CHO) cells expressing human GnRH receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50101236(2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-3-yl-bu...)
Affinity DataIC50:  61nMAssay Description:Inhibition of GnRH-stimulated phosphatidyinositol (PI) hydrolysis in cloned chinese hamster ovary (CHO) cells expressing human GnRH receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed