BDBM50101243 2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butylamino)-ethyl]-1H-indole-5-carboxylic acid diisopropylamide::CHEMBL49412

SMILES CC(C)N(C(C)C)C(=O)c1ccc2[nH]c(c(CCNCCCCc3ccncc3)c2c1)-c1cc(C)cc(C)c1

InChI Key InChIKey=WHRZIVXJZOCRBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50101243   

TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50101243(2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butyl...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of GnRH-stimulated phosphatidyinositol (PI) hydrolysis in cloned chinese hamster ovary (CHO) cells expressing human GnRH receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50101243(2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-butyl...)
Affinity DataIC50:  400nMAssay Description:Inhibition of GnRH-stimulated luteinizing hormone (LH) release in rat pituitary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed