BDBM50101261 CHEMBL295140::{(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-[4-methoxy-2-(1H-tetrazol-5-ylmethoxy)-phenyl]-1,3-dihydro-isoindol-2-yl}-acetic acid

SMILES CCOc1ccc2c(c1)[C@@H](c1ccc(OC)cc1OCc1nnn[nH]1)N(CC(=O)O)[C@@H]2c1ccc2c(c1)OCO2

InChI Key InChIKey=DKZVMSFPFHQYJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101261   

TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101261BDBM50101261({(1R,3S)-1-Benzo[1,3]dioxol-5-yl-5-ethoxy-3-[4-met...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibition of [125I]ET1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed