BDBM50101264 CHEMBL298664::[(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-(2-carboxymethoxy-3,4-dimethoxy-phenyl)-5-ethoxy-1,3-dihydro-isoindol-2-yl]-acetic acid

SMILES CCOc1ccc2[C@H](N(CC(O)=O)[C@H](c2c1)c1ccc(OC)c(OC)c1OCC(O)=O)c1ccc2OCOc2c1

InChI Key InChIKey=AEBFVYQCTDATBZ-SXOMAYOGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101264   

TargetEndothelin-1 receptor(Human)
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50101264(CHEMBL298664 | [(1R,3R)-1-Benzo[1,3]dioxol-5-yl-3-...)
Affinity DataIC50:  96nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to CHO cells expressing recombinant human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed