BDBM50101510 (R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4*-hydroxy-2-[3-(4-trifluoromethyl-phenyl)-propyl]-succinamide::CHEMBL76519::N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4*-hydroxy-2-[3-(4-trifluoromethyl-phenyl)-propyl]-succinamide

SMILES ONC(=O)C[C@@H](CCCc1ccc(cc1)C(F)(F)F)C(=O)N[C@@H](CC1CCCCC1)C(=O)NCCc1ccccc1

InChI Key InChIKey=YGJCNDHMYMIUBJ-VPUSJEBWSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101510   

Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101510((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  0.300nMAssay Description:Inhibitory constant against matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101510((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of the gelatinase-A enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101510((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  90nMAssay Description:Inhibition of the stromelysin enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50101510((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  90.3nMAssay Description:Inhibitory constant against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101510((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibitory constant against matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101510((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of the collagenase enzyme.More data for this Ligand-Target Pair
In DepthDetails Article