BDBM50101530 (R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4*-hydroxy-2-[3-(4-methoxy-phenyl)-propyl]-succinamide::CHEMBL310037::N*1*-(2-Cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4*-hydroxy-2-[3-(4-methoxy-phenyl)-propyl]-succinamide

SMILES COc1ccc(CCC[C@H](CC(=O)NO)C(=O)N[C@@H](CC2CCCCC2)C(=O)NCCc2ccccc2)cc1

InChI Key InChIKey=AAMWPNSLYMJRGM-IAPPQJPRSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101530   

Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101530((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  0.0600nMAssay Description:Inhibitory constant against matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target72 kDa type IV collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101530((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of the gelatinase-A enzyme.More data for this Ligand-Target Pair
In DepthDetails Article

TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101530((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  4.16nMAssay Description:Inhibitory constant against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetStromelysin-1(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101530((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  4.20nMAssay Description:Inhibition of the stromelysin enzyme.More data for this Ligand-Target Pair
In DepthDetails Article

TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101530((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibitory constant against matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetInterstitial collagenase(Human)
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101530((R)-N*1*-((S)-2-Cyclohexyl-1-phenethylcarbamoyl-et...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of the collagenase enzyme.More data for this Ligand-Target Pair
In DepthDetails Article