BDBM50101726 CHEMBL305160::[3-(Methanesulfonyl-methyl-amino)-cyclohexyl]-(4'-methoxy-biphenyl-4-sulfonylamino)-acetic acid

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)NC(C1CCCC(C1)N(C)S(C)(=O)=O)C(O)=O

InChI Key InChIKey=CPDXTLZUFAYJLD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101726   

Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101726([3-(Methanesulfonyl-methyl-amino)-cyclohexyl]-(4'-...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101726([3-(Methanesulfonyl-methyl-amino)-cyclohexyl]-(4'-...)
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101726([3-(Methanesulfonyl-methyl-amino)-cyclohexyl]-(4'-...)
Affinity DataIC50: 560nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101726([3-(Methanesulfonyl-methyl-amino)-cyclohexyl]-(4'-...)
Affinity DataIC50: 4.66E+3nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101726([3-(Methanesulfonyl-methyl-amino)-cyclohexyl]-(4'-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory concentration against Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed